美国监管机构批准白血病基因疗法
文章来源:未知 文章作者:enread 发布时间:2017-09-14 00:28 字体: [ ]  进入论坛
(单词翻译:双击或拖选)
US regulators on Wednesday approved the first gene1 therapy against cancer - a treatment that uses a patient's own immune cells to fight leukemia - opening a new era in the fight against one of the world's top killers2
 
美国监管机构于8月30日批准了首个对抗癌症的基因治疗手段——使用患者的免疫细胞对抗白血病。白血病是世界上致死率最高的疾病之一,该治疗手段开启了对抗白血病的新纪元。
 
The treatment is made by Novartis and is called Kymriah. 
 
This type of anti-cancer immunotherapy, known as a CAR-T cell therapy, was known by CTL019 until now. 
 
"This marks the first-ever CAR-T cell therapy to be approved anywhere in the world," Novartis CEO Joseph Jimenez told reporters on a conference call. 
 
"It uses a new approach that is wholly personalized by using a patient's own T-cells." 
 
Kymriah was approved by the US Food and Drug Administration for children and young adult patients up to age 25 with a form of acute lymphoblastic leukemia (ALL). 
 
To qualify for treatment, patients must have B-cell precursor3 ALL that is refractory4, or the patient has relapsed at least twice. 
 
The FDA described the approval as "a historic action" and a "new approach to the treatment of cancer and other serious and life-threatening diseases," said a statement.


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1 gene WgKxx     
n.遗传因子,基因
参考例句:
  1. A single gene may have many effects.单一基因可能具有很多种效应。
  2. The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 killers c1a8ff788475e2c3424ec8d3f91dd856     
凶手( killer的名词复数 ); 消灭…者; 致命物; 极难的事
参考例句:
  1. He remained steadfast in his determination to bring the killers to justice. 他要将杀人凶手绳之以法的决心一直没有动摇。
  2. They were professional killers who did in John. 杀死约翰的这些人是职业杀手。
3 precursor rPOx1     
n.先驱者;前辈;前任;预兆;先兆
参考例句:
  1. Error is often the precursor of what is correct.错误常常是正确的先导。
  2. He said that the deal should not be seen as a precursor to a merger.他说该笔交易不应该被看作是合并的前兆。
4 refractory GCOyK     
adj.倔强的,难驾驭的
参考例句:
  1. He is a very refractory child.他是一个很倔强的孩子。
  2. Silicate minerals are characteristically refractory and difficult to break down.硅酸盐矿物的特点是耐熔和难以分离。
TAG标签: cancer gene therapy
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