安吉丽娜·朱莉:My Medical Choice
文章来源:未知 文章作者:enread 发布时间:2013-05-19 06:23 字体: [ ]  进入论坛
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MY MOTHER fought cancer for almost a decade and died at 56. She held out long enough to meet the first of her grandchildren and to hold them in her arms. But my other children will never have the chance to know her and experience how loving and gracious she was.
 
We often speak of "Mommy's mommy," and I find myself trying to explain the illness that took her away from us. They have asked if the same could happen to me. I have always told them not to worry, but the truth is I carry a "faulty" gene1, BRCA1, which sharply increases my risk of developing breast cancer and ovarian cancer.
 
My doctors estimated that I had an 87 percent risk of breast cancer and a 50 percent risk of ovarian cancer, although the risk is different in the case of each woman.
 
Only a fraction of breast cancers result from an inherited gene mutation2. Those with a defect in BRCA1 have a 65 percent risk of getting it, on average.
 
Once I knew that this was my reality, I decided3 to be proactive and to minimize the risk as much I could. I made a decision to have a preventive double mastectomy(乳房切除术). I started with the breasts, as my risk of breast cancer is higher than my risk of ovarian cancer, and the surgery is more complex.
 
On April 27, I finished the three months of medical procedures that the mastectomies involved. During that time I have been able to keep this private and to carry on with my work.
 
But I am writing about it now because I hope that other women can benefit from my experience. Cancer is still a word that strikes fear into people's hearts, producing a deep sense of powerlessness. But today it is possible to find out through a blood test whether you are highly susceptible4 to breast and ovarian cancer, and then take action.
 
My own process began on Feb. 2 with a procedure known as a "nipple(乳头) delay," which rules out disease in the breast ducts behind the nipple and draws extra blood flow to the area. This causes some pain and a lot of bruising5, but it increases the chance of saving the nipple.
 
Two weeks later I had the major surgery, where the breast tissue is removed and temporary fillers are put in place. The operation can take eight hours. You wake up with drain tubes and expanders in your breasts. It does feel like a scene out of a science-fiction film. But days after surgery you can be back to a normal life.
 
Nine weeks later, the final surgery is completed with the reconstruction6 of the breasts with an implant7. There have been many advances in this procedure in the last few years, and the results can be beautiful.
 
I wanted to write this to tell other women that the decision to have a mastectomy was not easy. But it is one I am very happy that I made. My chances of developing breast cancer have dropped from 87 percent to under 5 percent. I can tell my children that they don't need to fear they will lose me to breast cancer.
 
It is reassuring8 that they see nothing that makes them uncomfortable. They can see my small scars and that's it. Everything else is just Mommy, the same as she always was. And they know that I love them and will do anything to be with them as long as I can. On a personal note, I do not feel any less of a woman. I feel empowered that I made a strong choice that in no way diminishes my femininity.
 
I am fortunate to have a partner, Brad Pitt, who is so loving and supportive. So to anyone who has a wife or girlfriend going through this, know that you are a very important part of the transition. Brad was at the Pink Lotus Breast Center, where I was treated, for every minute of the surgeries. We managed to find moments to laugh together. We knew this was the right thing to do for our family and that it would bring us closer. And it has.
 
For any woman reading this, I hope it helps you to know you have options. I want to encourage every woman, especially if you have a family history of breast or ovarian cancer, to seek out the information and medical experts who can help you through this aspect of your life, and to make your own informed choices.
 
I acknowledge that there are many wonderful holistic9 doctors working on alternatives to surgery. My own regimen will be posted in due course on the Web site of the Pink Lotus Breast Center. I hope that this will be helpful to other women.
 
Breast cancer alone kills some 458,000 people each year, according to the World Health Organization, mainly in low- and middle-income countries. It has got to be a priority to ensure that more women can access gene testing and lifesaving preventive treatment, whatever their means and background, wherever they live. The cost of testing for BRCA1 and BRCA2, at more than $3,000 in the United States, remains10 an obstacle for many women.
 
I choose not to keep my story private because there are many women who do not know that they might be living under the shadow of cancer. It is my hope that they, too, will be able to get gene tested, and that if they have a high risk they, too, will know that they have strong options.
 
Life comes with many challenges. The ones that should not scare us are the ones we can take on and take control of.


点击收听单词发音收听单词发音  

1 gene WgKxx     
n.遗传因子,基因
参考例句:
  1. A single gene may have many effects.单一基因可能具有很多种效应。
  2. The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 mutation t1PyM     
n.变化,变异,转变
参考例句:
  1. People who have this mutation need less sleep than others.有这种突变的人需要的睡眠比其他人少。
  2. So far the discussion has centered entirely around mutation in the strict sense.到目前为止,严格来讲,讨论完全集中于围绕突变问题上。
3 decided lvqzZd     
adj.决定了的,坚决的;明显的,明确的
参考例句:
  1. This gave them a decided advantage over their opponents.这使他们比对手具有明显的优势。
  2. There is a decided difference between British and Chinese way of greeting.英国人和中国人打招呼的方式有很明显的区别。
4 susceptible 4rrw7     
adj.过敏的,敏感的;易动感情的,易受感动的
参考例句:
  1. Children are more susceptible than adults.孩子比成人易受感动。
  2. We are all susceptible to advertising.我们都易受广告的影响。
5 bruising 5310e51c1a6e8b086b8fc68e716b0925     
adj.殊死的;十分激烈的v.擦伤(bruise的现在分词形式)
参考例句:
  1. He suffered cracked ribs and bruising. 他断了肋骨还有挫伤。
  2. He slipped and fell, badly bruising an elbow. 他滑倒了,一只胳膊肘严重擦伤。 来自辞典例句
6 reconstruction 3U6xb     
n.重建,再现,复原
参考例句:
  1. The country faces a huge task of national reconstruction following the war.战后,该国面临着重建家园的艰巨任务。
  2. In the period of reconstruction,technique decides everything.在重建时期,技术决定一切。
7 implant YaBxT     
vt.注入,植入,灌输
参考例句:
  1. A good teacher should implant high ideals in children.好教师应该把高尚理想灌输给孩子们。
  2. The operation to implant the artificial heart took two hours.人工心脏植入手术花费了两小时。
8 reassuring vkbzHi     
a.使人消除恐惧和疑虑的,使人放心的
参考例句:
  1. He gave her a reassuring pat on the shoulder. 他轻拍了一下她的肩膀让她放心。
  2. With a reassuring pat on her arm, he left. 他鼓励地拍了拍她的手臂就离开了。
9 holistic OQqzJ     
adj.从整体着眼的,全面的
参考例句:
  1. There is a fundamental ambiguity in the use of word "whole" in recent holistic literature.在近代的整体主义著作中,“整体”这个词的用法极其含混。
  2. In so far as historicism is technological,its approach is not piecemeal,but "holistic".仅就历史决定论是一种技术而论,它的方法不是渐进的,而是“整体主义的”。
10 remains 1kMzTy     
n.剩余物,残留物;遗体,遗迹
参考例句:
  1. He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
  2. The remains of the meal were fed to the dog.残羹剩饭喂狗了。
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